top of page
Search

Research Roundup: June 20, 2023



Best of cannabinoid science this week...


An analysis of the barriers of access to CBD for children with neuro disabilities Barriers for access to cannabidiol as a treatment option for children with neuro-diverse disabilities: A qualitative key informants method https://www.sciencedirect.com/science/article/abs/pii/S235255252300035X


On the efficacy of using CBD for treatment-resistant epilepsy Efficacy of cannabidiol in convulsive and nonconvulsive seizure types associated with treatment-resistant epilepsies in the Expanded Access Program https://pubmed.ncbi.nlm.nih.gov/37243404/


Top cannabinoid researchers on the lessons they've learned from the last 30 years of targeting the endocannabinoid system

Goods and bads of endocannabinoid system as a therapeutic target: Lessons learned after 30 years


In a dog with compulsive disorder, using cannabis & melatonin lowered their compulsive episodes Combining cannabis and melatonin treatment with a rehabilitation program improved symptoms in a dog with compulsive disorder: A case report https://pubmed.ncbi.nlm.nih.gov/37245289/


In a survey of equine industry professionals, the majority believed CBD should be legal in competition, that it provided benefits for the horses such as calming & many believed it to reduce inflammation as effectively as NSAIDs Industry perceptions of cannabidiol use in horses https://www.sciencedirect.com/science/article/abs/pii/S073708062300309X


A review of drugs to treat psychosis find help from CBD Use of psychoactive substances as a treatment for psychosis https://pubmed.ncbi.nlm.nih.gov/37231549/


In neurons, CBD protected them from the dopamine toxicity of paraquat via antioxidant & antiapoptotic (cellular suicide) effects, suggesting them as a treatment for Parkinson's disease Cannabidiol Protects Dopaminergic-like Neurons against Paraquat- and Maneb-Induced Cell Death through Safeguarding DJ-1CYS106 and Caspase 3 Independently of Cannabinoid Receptors: Relevance in Parkinson's Disease https://pubmed.ncbi.nlm.nih.gov/37220279/


In a mouse model of colitis, dietary CBD suppressed inflammation & enhanced gut barrier function via the PKA & AMPK signaling pathways Dietary cannabidiol activates PKA/ERK/AMPK signaling and attenuates chronic inflammation and leaky gut in DSS-induced colitis mice https://journals.physiology.org/doi/abs/10.1152/physiol.2023.38.S1.5789473

In a model of inflammatory bowel disease, white blood cell migration was inhibited by anandamide, CBD & AM-1241 (an activator of the CB2 receptor) Development of a new cannabinoid-based therapy to treat inflammatory bowel disease https://journals.physiology.org/doi/abs/10.1152/physiol.2023.38.S1.5733403

In mice, 8 weeks of CBG lowered their blood pressure Chronic cannabigerol administration lowers blood pressure in phenotypically normal mice https://journals.physiology.org/doi/abs/10.1152/physiol.2023.38.S1.5726031


In a mouse model of Alzheimer's, the cannabis terpenes linalool & cineol combined well with aerobic exercise to cause a protective effect via the genetic expression of Bdnf, Ngf & Creb The Effect of Linalool, Cineole, Beta bourbonin and Aerobic Exercises as Protective Approaches in Mice with Alzheimer's Disease https://jims.mui.ac.ir/article_30938.html?lang=en

댓글


bottom of page