top of page
nausea.jpg

Cannabinoid Hyperemesis Syndrome

Best reviews

2023: A review of the current science on cannabis hyperemesis syndrome
Cyclic Vomiting Syndrome and Cannabis Hyperemesis Syndrome: The State of the Science
https://pubmed.ncbi.nlm.nih.gov/37074964/


2023: A review on how to manage cannabinoid hyperemesis syndrome
Cyclic Vomiting Syndrome, Dumping, and Marijuana-Induced Hyperemesis Syndrome
https://link.springer.com/chapter/10.1007/978-3-031-19671-3_45

2023: For cannabinoid hyperemesis syndrome, a review of seven articles on using dopamine antagonists & topical capsaicin
Dopamine antagonists and topical capsaicin for cannabis hyperemesis syndrome (CHS) in the emergency department: a systematic review of direct evidence
https://pubmed.ncbi.nlm.nih.gov/37391387/

2023: A case study of cannabinoid hyperemesis syndrome causing acute kidney injury + a review of the literature
A Case of Cannabinoid Hyperemesis Syndrome and Acute Kidney Injury: A Review of the Literature
https://pubmed.ncbi.nlm.nih.gov/36865973/

2022: For cannabinoid hyperemesis syndrome, treatment with haloperidol (the most common antipsychotic medication in the US)
Haloperidol as a treatment option in cannabinoid hyperemesis syndrome
https://pubmed.ncbi.nlm.nih.gov/36514445/

2022: On the rise of cannabinoid hyperemesis syndrome in North America
Cannabinoid hyperemesis syndrome in North America: evaluation of health burden and treatment prevalence
https://pubmed.ncbi.nlm.nih.gov/36307209

2022: A review of the history of cannabinoid hyperemesis syndrome
Cannabinoid Hyperemesis Syndrome: Lighting Up an Emergency Department Near You
https://pubmed.ncbi.nlm.nih.gov/36035580

2022: A review of how to handle cannabinoid hyperemesis syndrome (cyclical vomiting) & withdrawal from cannabis
Cannabinoid hyperemesis syndrome and cannabis withdrawal syndrome: a review of the management of cannabis-related syndrome in the emergency department
https://pubmed.ncbi.nlm.nih.gov/36076180

2022: A summary on the diagnosis & treatment of cannabinoid hyperemesis syndrome
Last Gag with Mary Jane: Cannabinoid Hyperemesis Syndrome (CHS)
https://emottawablog.com/2022/07/last-gag-with-mary-jane-cannabinoid-hyperemesis-syndrome-chs

2022: A review on treating cannabinoid hyperemesis syndrome (uncontrolled cyclical vomiting & abdominal pain in cannabis smokers)
Pharmacological management of cannabinoid hyperemesis syndrome: an update of the clinical literature
https://pubmed.ncbi.nlm.nih.gov/35311429/

 

2022: On how to help adolescents who have cannabinoid hyperemesis (cyclical vomiting)
Paediatric cannabinoid hyperemesis
https://pubmed.ncbi.nlm.nih.gov/35946907

2021:

A Systematic Review on Cannabis Hyperemesis Syndrome and its Management Options

https://pubmed.ncbi.nlm.nih.gov/34724666/

2021:

ED Management of Cannabinoid Hyperemesis Syndrome: Breaking the Cycle

https://www.aliem.com/breaking-cycle-ed-management-cannabinoid-hyperemesis-syndrome/

2021: Two letters to the editor about how cannabis hyperemesis syndrome (uncontrolled cyclical vomiting from cannabis consumption) might be caused by the plant pathogen ‘hop latent viroid’

Fool’s gold: diseased marijuana and cannabis hyperemesis syndrome

https://jim.bmj.com/content/69/5/1063.full

Response to 'Fool’s gold: diseased marijuana and cannabis hyperemesis syndrome'

https://jim.bmj.com/content/jim/69/5/1065.full.pdf

2021:

Cannabinoid Hyperemesis Syndrome in Pediatrics: An Emerging Problem

https://pubmed.ncbi.nlm.nih.gov/34470869/

2021:

A focused, longitudinal analysis of cannabinoid hyperemesis syndrome symptomatology

https://pubmed.ncbi.nlm.nih.gov/34325648/

2021:

Cannabinoid Hyperemesis Syndrome: A Review of the Presentation and Treatment

https://pubmed.ncbi.nlm.nih.gov/33712244/

2020: A review on how to diagnose & treat cannabinoid hyperemesis syndrome in teens

Diagnosis and Acute Management of Adolescent Cannabinoid Hyperemesis Syndrome: A Systematic Review

https://pubmed.ncbi.nlm.nih.gov/33036874/

2020:

Cannabinoid hyperemesis syndrome in the pregnant patient: clinical case and literature review

https://pubmed.ncbi.nlm.nih.gov/33115404/

2020:

Management of Cannabinoid Hyperemesis Syndrome: Focus on Capsaicin

https://pubmed.ncbi.nlm.nih.gov/32613883/

2020: A new review of cannabis hyperemesis syndrome

Endocannabinoid system and cannabis hyperemesis syndrome: a narrative update

https://pubmed.ncbi.nlm.nih.gov/33208685/

2020:

Cannabinoid hyperemesis syndrome: definition, pathophysiology, clinical spectrum, insights into acute and long-term management

https://pubmed.ncbi.nlm.nih.gov/33115959/

2020:

Cannabinoid hyperemesis syndrome: the conundrum is here to stay

https://jim.bmj.com/content/jim/early/2020/10/28/jim-2020-001669.full.pdf

2020:

Cannabis Hyperemesis Syndrome: A Still Under-Recognized Syndrome

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7213821/

2020: In humans, a review of the potential mechanisms causing cannabinoid hyperemesis syndrome (violent vomiting & pain from high amounts of cannabis use)

Cannabinoid Hyperemesis Syndrome: A Review of Potential Mechanisms

https://www.liebertpub.com/doi/abs/10.1089/can.2019.0059

2019: In cannabinoid-induced hyperemesis (where you can't stop vomiting after consuming cannabis), topical capsaicin may help

Topical Capsaicin for Treatment of Cannabinoid Induced Hyperemesis

https://digitalshowcase.lynchburg.edu/dmscjournal/vol1/iss4/48/

2019: Capsaicin may be helpful in cannabis hyperemesis syndrome

Efficacy and safety of topical capsaicin for cannabinoid hyperemesis syndrome in the emergency department

https://www.ncbi.nlm.nih.gov/pubmed/31482758

Timeline of Research

2023: In an excellent use of scraping Reddit, this analysis of posts on cannabinoid hyperemesis syndrome points to triggers & treatments not often mentioned in the scientific literature
An analysis of cannabinoid hyperemesis syndrome Reddit posts and themes
https://pubmed.ncbi.nlm.nih.gov/37014024/
“Reddit posts for cannabinoid hyperemesis syndrome provide a valuable source of community discussion and individual reports of people experiencing cannabinoid hyperemesis syndrome. Mental health and alcohol were frequently reported triggers within the posts but are not often identified in the literature. While many of the therapies mentioned are well documented, behavioral responses such as meditation and yoga have not been explored by the scientific literature.”

2023: In a chart review, they find that it’s worth trying 50 mg of Benadryl & 10 mg of Compazine for cannabinoid hyperemesis syndrome
Hyperemesis Cannabinoid Syndrome Chart Review
https://unthsc-ir.tdl.org/handle/20.500.12503/32141

2023: A case report of a young person with type-1 diabetes experiencing cannabinoid hyperemesis syndrome (uncontrolled cyclical vomiting)
Cannabinoid Hyperemesis Syndrome in a 23-Year-Old Woman with Uncontrolled Type 1 Diabetes Mellitus
https://pubmed.ncbi.nlm.nih.gov/36806029/

2023: In adolescents with cannabinoid hyperemesis syndrome, a comparison of the efficacy of traditional & nontraditional anti-emetics (anti-nausea medication)
Comparison of Antiemetics in the Management of Pediatric Cannabinoid Hyperemesis Syndrome
https://pubmed.ncbi.nlm.nih.gov/37303765/

2023: On the challenges of being pregnant & having cannabinoid hyperemesis syndrome
Cannabinoid hyperemesis syndrome in pregnancy: Challenges and opportunities
https://pubmed.ncbi.nlm.nih.gov/37259610/

2023: In a case study of cannabinoid hyperemesis syndrome, the patient experienced repeated severe burns from their compulsive use of hot baths to lower the vomiting
Recurrent Severe Burns Due to Cannabinoid Hyperemesis Syndrome
https://pubmed.ncbi.nlm.nih.gov/36879712/

2023: An observational study following patients with cannabinoid hyperemesis syndrome for three months after their visit to an emergency room
Cannabinoid hyperemesis syndrome: clinical trajectories and patterns of use three months following a visit to the emergency department
https://pubmed.ncbi.nlm.nih.gov/37387520/

2023: In a child with epilepsy, a rare case of CBD causing cannabinoid hyperemesis syndrome
A Rare Case of Cannabinoid Hyperemesis Syndrome Secondary to Cannabidiol for Refractory Epilepsy
https://pubmed.ncbi.nlm.nih.gov/37181918/

2023: In patients with suspected cannabinoid hyperemesis syndrome, an analysis of their use patterns & blood cannabinoid profiles
Cannabis Use Patterns and Whole-Blood Cannabinoid Profiles of Emergency Department Patients With Suspected Cannabinoid Hyperemesis Syndrome
https://www.annemergmed.com/article/S0196-0644(23)00179-8/fulltext

2023: A sad survey on the difficult situation of people who might have cannabinoid hyperemesis syndrome
"I still partly think this is bullshit": A qualitative analysis of cannabinoid hyperemesis syndrome perceptions among people with chronic cannabis use and cyclic vomiting
https://pubmed.ncbi.nlm.nih.gov/36996524/

2023: A case report of cannabis hyperemesis syndrome along with recurrent kidney stones
A Case of a Patient With Cannabis Hyperemesis Syndrome Along With Recurrent Nephrolithiasis
https://pubmed.ncbi.nlm.nih.gov/37159782/

 

2023: A case report of recurrent diabetic ketoacidosis (dangerous levels of ketones from the breakdown of fats instead of sugars) eventually determined to be from cannabinoid hyperemesis syndrome
Unexpected cause of recurrent diabetic ketoacidosis in type 1 diabetes: a case report
https://pubmed.ncbi.nlm.nih.gov/37400799/

2023: A case report of a woman with cannabinoid hyperemesis syndrome whose use of a heating pad for relief led to bullous erythema ab igne (a skin disorder caused by chronic exposure to heat)
Erythema Ab Igne Associated With Cannabinoid Hyperemesis Syndrome
https://pubmed.ncbi.nlm.nih.gov/37270269/

2023: In Massachusetts, legalization saw a rise in cannabinoid hyperemesis syndrome admissions
Rising Inpatient Utilization and Costs of Cannabis Hyperemesis Syndrome Hospitalizations in Massachusetts After Cannabis Legalization
https://pubmed.ncbi.nlm.nih.gov/37224284/

2023: Using natural language processing to improve the estimates of cannabinoid hyperemesis syndrome
Natural language processing improves estimates of the epidemiology of cannabinoid hyperemesis syndrome
https://pubmed.ncbi.nlm.nih.gov/37349236/

2022: In rural Nepal, a case of undiagnosed cannabinoid hyperemesis syndrome
Case report: A case of undiagnosed cannabinoid hyperemesis syndrome in rural part of Nepal
https://pubmed.ncbi.nlm.nih.gov/36582911/

2022: A case study of a healthy young person with chest problems from cannabinoid hyperemesis syndrome
Pneumomediastinum and Pneumorrhachis Associated With Cannabinoid Hyperemesis Syndrome
https://pubmed.ncbi.nlm.nih.gov/36632263/

2022: A case report of a young person with cannabinoid hyperemesis syndrome who experienced air in the body cavity & around the spine
Pneumomediastinum and Pneumorrhachis Associated With Cannabinoid Hyperemesis Syndrome
https://www.cureus.com/articles/125647-pneumomediastinum-and-pneumorrhachis-associated-with-cannabinoid-hyperemesis-syndrome

2022: A case report of a 17-year-female with cannabinoid hyperemesis syndrome
Cannabinoid Hyperemesis Syndrome Complicated by Pneumomediastinum: Implications for Pediatric Surgeons
https://pubmed.ncbi.nlm.nih.gov/36438163/

2022: For treating cannabinoid hyperemesis syndrome (intense cyclical vomiting), this study of 17 patients found droperidol (am anti-nausea injection) helpful
32 Droperidol on Prevention of Emesis from Cannabinoid Hyperemesis Syndrome (DOPE Study)
https://www.annemergmed.com/article/S0196-0644(22)00639-4/fulltext

2022: In Canada’s most populous province, the legalization of cannabis saw a large increase to the emergency room for cannabis hyperemesis syndrome
Changes in Emergency Department Visits for Cannabis Hyperemesis Syndrome Following Recreational Cannabis Legalization and Subsequent Commercialization in Ontario, Canada
https://pubmed.ncbi.nlm.nih.gov/36112372

2022: 3 teens with cannabis hyperemesis syndrome & hypophosphatemia (low blood levels of phosphate, used for energy & nerve function)
Cannabinoid Hyperemesis Syndrome and Hypophosphatemia in Adolescents
https://pubmed.ncbi.nlm.nih.gov/37168463/

2022: A case report of a young cannabis user who died of cyclic vomiting
Death of a young woman with cyclic vomiting: a case report
https://pubmed.ncbi.nlm.nih.gov/34735682

2022: In a pregnant patient, using haloperidol to treat cannabis hyperemesis syndrome
Treatment of Cannabis Hyperemesis Syndrome Using Haloperidol in a Pregnant Patient: Case Report
https://pubmed.ncbi.nlm.nih.gov/35943399

2022: On how to help adolescents who have cannabinoid hyperemesis (cyclical vomiting)
Paediatric cannabinoid hyperemesis
https://pubmed.ncbi.nlm.nih.gov/35946907

2022: A case report of a young cannabis user who died of cyclic vomiting
Death of a young woman with cyclic vomiting: a case report
https://pubmed.ncbi.nlm.nih.gov/34735682

2022: In Canada’s most populous province, the legalization of cannabis saw a large increase to the emergency room for cannabis hyperemesis syndrome
Changes in Emergency Department Visits for Cannabis Hyperemesis Syndrome Following Recreational Cannabis Legalization and Subsequent Commercialization in Ontario, Canada
https://pubmed.ncbi.nlm.nih.gov/36112372

2022: 3 teens with cannabis hyperemesis syndrome & hypophosphatemia (low blood levels of phosphate, used for energy & nerve function)
Cannabinoid Hyperemesis Syndrome and Hypophosphatemia in Adolescents
https://journals.lww.com/jpgnr/Fulltext/2022/11000/Cannabinoid_Hyperemesis_Syndrome_and.3.aspx

2022: In a pregnant patient, using haloperidol to treat cannabis hyperemesis syndrome
Treatment of Cannabis Hyperemesis Syndrome Using Haloperidol in a Pregnant Patient: Case Report
https://pubmed.ncbi.nlm.nih.gov/35943399

2022: In a cancer patient, after years of nabilone (synthetic THC) to manage her pain, increasing the dosage during her chemotherapy treatments led to cannabinoid hyperemesis syndrome & cyclical vomiting
A case report on cannabinoid hyperemesis syndrome in palliative care: how good intentions can go wrong
https://pubmed.ncbi.nlm.nih.gov/35504245/

2022:

Cannabinoid hyperemesis syndrome: A 6-year audit of adult presentations to an urban district hospital

https://pubmed.ncbi.nlm.nih.gov/35199462/

2022: diabetes & hyperemesis

Differentiating Diabetic Ketoacidosis and Hyperglycemic Ketosis Due to Cannabis Hyperemesis Syndrome in Adults With Type 1 Diabetes

https://pubmed.ncbi.nlm.nih.gov/34880067/

2021: On using topical capsaicin for treating cannabinoid hyperemesis syndrome (uncontrolled cyclical vomiting)
Is capsaicin an effective treatment for cannabinoid hyperemesis syndrome?
https://journals.lww.com/ebp/Citation/2021/12000/Is_capsaicin_an_effective_treatment_for.33.aspx

 

2021: A case of cannabis hyperemesis syndrome that caused Wilkie’s syndrome aka Superior mesenteric artery syndrome (a compression of the upper part of the small intestine just below the stomach)
A Rare Case of Superior Mesenteric Artery (SMA) Syndrome, or Wilkie's Syndrome (WS) in a Patient With Cannabinoid Hyperemesis Syndrome (CHS)
https://journals.lww.com/ajg/Fulltext/2021/10001/S3700_A_Rare_Case_of_Superior_Mesenteric_Artery.3704.aspx

2021:

CANNABINOID HYPEREMESIS SYNDROME AND CHRONIC VAPING USE COMPLICATED BY MULTISYSTEM ORGAN FAILURE

https://journal.chestnet.org/article/S0012-3692(21)02295-9/fulltext

2021:

QTc prolongation in cannabis hyperemesis syndrome patients exposed to antiemetics: A retrospective chart review

https://pubmed.ncbi.nlm.nih.gov/34607736/

2021:

Cannabinoid Hyperemesis Syndrome: A Case Report of an Underdiagnosed Condition

https://pubmed.ncbi.nlm.nih.gov/34901450/

2021:

Cannabinoid Hyperemesis Syndrome Survey and Genomic Investigation

https://pubmed.ncbi.nlm.nih.gov/34227878/

2021:

Treatment of Cannabinoid Hyperemesis Syndrome-Associated Nausea with Haloperidol: A Case Report

https://www.scirp.org/journal/paperinformation.aspx?paperid=110002

2021:

Aortic Mural Thrombus and Acute Coronary Syndrome in a Patient With Cannabinoid Hyperemesis Syndrome

https://pubmed.ncbi.nlm.nih.gov/34317606/

2021:

Haloperidol as an anti-emetic for Cannabis Hyperemesis Syndrome in the ED

https://pubmed.ncbi.nlm.nih.gov/33835429/

2021:

The role of cytochrome P450 enzyme genetic variants in cannabis hyperemesis syndrome-A case report

https://pubmed.ncbi.nlm.nih.gov/33740842/

2021:

Efficacy of topical capsaicin for the treatment of cannabinoid hyperemesis syndrome: A retrospective cohort study

https://pubmed.ncbi.nlm.nih.gov/33561623/

2021:

Cannabinoid hyperemesis syndrome in two French emergency departments: a prospective cohort

https://pubmed.ncbi.nlm.nih.gov/33423327/

2020: A case report of cannabinoid hyperemesis syndrome causing Hamman’s syndrome (air in the skin & center of the chest cavity causing pain)
Hamman’s Syndrome or Boerhaave Syndrome? A Curious Case of Pneumomediastinum Triggered by Cannabinoid Hyperemesis Syndrome
https://journals.lww.com/ajg/Fulltext/2020/10001/S1954_Hamman_s_Syndrome_or_Boerhaave_Syndrome__A.1954.aspx

2020: A case series of 3 patients with cannabinoid hyperemesis syndrome during pregnancy
HYPEREMESIS CANNABINOID SYNDROME IN PREGNANCY: A CASE SERIES
https://www.eventscribe.com/2020/CLP/fsPopup.asp?efp=VEtETlZaQUwxMTgwMw&PosterID=307534&rnd=0.4361652&mode=posterinfo

2020:

Topical Capsaicin for Treating Cannabinoid Hyperemesis Syndrome

https://pubmed.ncbi.nlm.nih.gov/33294233/

2020:

Recurrent Hospitalization for Cannabinoid Hyperemesis Syndrome in an Adolescent

https://jjgastrohepto.org/pdf/JJGH-v4-1358.pdf

2020:

Cannabinoid Hyperemesis Syndrome: An Unexpected Problem in an Unusual Setting-A Case Report

https://pubmed.ncbi.nlm.nih.gov/32472123/

2020: In the last 10 years, this center has seen 34 adolescents with cannabis hyperemesis syndrome

Pediatric Cannabinoid Hyperemesis: A Single Institution 10-Year Case Series

https://www.sciencedirect.com/science/article/abs/pii/S1054139X20305772

2020: A small double-blind trial of using capsaicin cream for treating cannabinoid hyperemesis syndrome

A Pilot Trial of Topical Capsaicin Cream for Treatment of Cannabinoid Hyperemesis Syndrome

https://onlinelibrary.wiley.com/doi/abs/10.1111/acem.14062

2020: Case presentation of a patient with cannabinoid hyperemesis syndrome & advice on what to look at in this relatively new clinical condition

Marijuana Use: Early Recognition for a Cannabinoid Hyperemesis Syndrome

https://www.ncbi.nlm.nih.gov/pubmed/32000189

2020: A Dutch patient with cannabinoid hyperemesis syndrome - as usual, the best relief came from hot baths

[A patient with acute abdominal pain and vomiting due to the cannabinoid hyperemesis syndrome]

https://www.ncbi.nlm.nih.gov/pubmed/31994714

2019: CB1 and mu-opioid polymorphisms (genetic differences) are associated with the risk of experiencing cyclic vomiting syndrome

Cannabinoid Receptor Type 1 and mu-Opioid Receptor Polymorphisms Are Associated With Cyclic Vomiting Syndrome

https://www.practiceupdate.com/content/cannabinoid-receptor-type-1-and-mu-opioid-receptor-polymorphisms-are-associated-with-cyclic-vomiting-syndrome/51373

bottom of page