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Research Roundup: July 11, 2023

Best of cannabinoid science this week...

In people with untreated high blood pressure, 24 hours of CBD significantly lowered their systolic pressure, arterial pressure & arterial stiffness The Influence of Oral Cannabidiol on 24-h Ambulatory Blood Pressure and Arterial Stiffness in Untreated Hypertension: A Double-Blind, Placebo-Controlled, Cross-Over Pilot Study

and the ability of CBD to lower blood pressure seems linked to serum levels of urotensin (the strongest known vasoconstrictor (besides my ex-wife)) Effects of CBD supplementation on ambulatory blood pressure and serum urotensin-II concentrations in Caucasian patients with essential hypertension: A sub-analysis of the HYPER-H21-4 trial

In epilepsy patients, the quality-of-life improvement from Epidiolex (pharmaceutical CBD) Quality improvement study in epilepsy patients treated with Epidiolex®

A review on the therapeutic uses of purified CBD

The therapeutic potential of purified cannabidiol

A review of using CBD to treat schizophrenia,

Cannabidiol as a Treatment for Schizophrenia


Current Evidence of Cannabidiol's Potential as an Anxiolytic Agent


Therapeutic Profile of Cannabidiol in the Broad Symptomatology of Autism Spectrum Disorder: Evidence From Basic Science to Clinical Approaches

and neuropathic facial pain The role of cannabidiol in modulating chronic neuropathic orofacial pain

In a review of the rare complex epilepsy known as Doose syndrome, they highlight CBD as a promising new treatment A MINI REVIEW OF DOOSE SYNDROME: CLINICAL MANIFESTATIONS, DIAGNOSIS, AND TREATMENT

An editorial on using CBD in psychiatric practice Cannabidiol (CBD) in psychiatric clinical practice: Current data

In stressed rats, a broad-spectrum hemp extract (no THC) lowered the biomarkers for oxidative stress Effect of Broad-Spectrum Hemp Extract on Neurobehavioral Activity on the Immobilization Stress-Induced Model in Sprague Dawley Rats

In a mouse model of migraines, CBD helped with the pain though it only helped the males with the related anxiety & pain behaviors Preclinical effects of cannabidiol in an experimental model of migraine

In a mouse model of a urinary tract infection, β-caryophyllene (one of the most common terpenes in cannabis) reduced bacteria in the urine & bladder tissues as well as reducing bladder inflammation & improving pain behaviors Antibacterial and Analgesic Properties of Beta-Caryophyllene in a Murine Urinary Tract Infection Model


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