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Research Roundup: Jan 24, 2022

Best of cannabinoid science this week...

In a sleep diary study, cannabis use was associated with improved sleep quality Cannabis use and sleep quality in daily life: An electronic daily diary study of adults starting cannabis for health concerns

In mice with high blood pressure, one month of cannabis oil reduced their hypertension & improved their network of mitochondria (powerhouse of the cell) probably via its antioxidant effects Cannabis oil one-month oral treatment given to spontaneously hypertensive rats (SHR): Could it be a promising therapeutic strategy for hypertensive cardiac hypertrophy?

CBD is protective of the heart in several diseases via its antioxidant & cardioprotective effects Treatment with Cannabidiol Results in an Antioxidant and Cardioprotective Effect in Several Pathophysiologies

In a rat model of obesity, CBD rich hemp extracts protected the heart via the inhibition of the transport of adenosine (a messenger of protein synthesis) The effect of a long-term treatment with cannabidiol-rich hemp extract oil on the adenosinergic system of the zucker diabetic fatty (ZDF) rat atrium

In a mouse model of nerve pain, CBD-rich extract lowered their pain sensitivity via the CB2 receptors of the microglia (immune guardian cells of the brain) Cannabidiol-rich non-psychotropic Cannabis sativa L. oils attenuate peripheral neuropathy symptoms by regulation of CB2-mediated microglial neuroinflammation

In skin connective tissue, both THC & CBD decreased aging & improved wound healing more effectively than the top skin ingredients they were tested against Phytocannabinoids Stimulate Rejuvenation and Prevent Cellular Senescence in Human Dermal Fibroblasts

A review of the effects of using cannabinoids for Parkinson's disease in animal models

Effects of cannabinoids in Parkinson's disease animal models: a systematic review and meta-analysis

In a roundworm model of Parkinson’s disease, CBDV lowered the aggregation of the α-synuclein plaques as well as oxidative stress & the death of dopamine producing neurons Cannabidivarin alleviates α-synuclein aggregation via DAF-16 in Caenorhabditis elegans

In a review of seven clinical trials on patients with MS, the use of Sativex (a 1:1 CBD: THC spray) caused no detrimental effects on cognitive function after 12 months of use Effects of SativexⓇ on cognitive function in patients with multiple sclerosis: A systematic review and meta-analysis


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