Best of cannabinoid science this week...
On why older adults in the US are using cannabis
PATTERNS OF MARIJUANA USE IN THE US OLDER ADULT POPULATION
“Multivariable regression analyses show that marijuana use declines with age (p<.001) and is lower among women (p<.001). Marijuana use among older adults is slightly lower in states where it is illegal compared to states that have legalized (4.6% vs. 7.1%, p<.001). Use of marijuana for medical reasons increases with age; nearly two-thirds of adults 80+ who use marijuana report doing so for medical reasons. Adults 80+ also report the highest frequency of use, likely reflecting greater medical need. The most common conditions reported among adults 50+ who use marijuana for medical reasons are arthritis (61%), depression (36%), asthma (20%), and COPD (18%).”
In hospice patients, cannabis combined well with opioids to reduce pain while lowering opioid usage & mitigating opioid toxicity
Medical Marijuana for Pain Management in Hospice Care as a Complementary Approach to Scheduled Opioids: A Single Arm Study
In a survey of Mexican patients with allergic respiratory diseases, the ones inhaling cannabis had less asthma
Cannabis use preferences among adult Mexican with allergic respiratory diseases: A cross-sectional study
An editorial on how seizures induced by fever may be treated by CBD via the FKBP51 protein (a stress regulator)
Cannabidiol for functional seizures (psychogenic nonepileptic seizures/attacks) and other stress-associated disorders
Cats well tolerated daily feeding of CBD at a dosage of 4 mg/kg
Healthy Cats Tolerate Long Term Daily Feeding of Cannabidiol
A review of using PEA for inflammation & immunomodulation
Therapeutic Use of Palmitoylethanolamide as an Anti-Inflammatory and Immunomodulator
A review on integrating cannabis products in the chronic pain treatment
Thoughtfully Integrating Cannabis Products Into Chronic Pain Treatment
And a review of four studies on cannabis for chronic pain
Use of cannabis and its derivates in chronic pain management: systematic review
For Parkinson's disease, a review of 95 articles on the use of cannabinoids
Beyond conventional therapy: cannabinoids as an alternative in parkinson's disease
For neuromuscular disorders, a review of the potential of the cannabinoids
Cannabinoids, Endocannabinoids, and Synthetic Cannabimimetic Molecules in Neuromuscular Disorders
A review of cannabis for the treatment of headaches
Cannabis Use in Headache Treatment: A Literature Review
A review of CBD for opioid use disorder
The Therapeutic Potential of Cannabidiol in Revolutionising Opioid Use Disorder Management
A review of the cannabinoids for mental health
Prospects for the Use of Cannabinoids in Mental Health
A review of the mechanisms that CBD uses in epilepsy to protect the brain
Enlightening Pharmacological Mechanisms of Cannabidiol in Epilepsy: A Comprehensive Review on their Neuroprotective Potential
In a mouse model of stroke, the anti-inflammatory & neuroprotective benefits of CBD involve the cyclin-dependent kinase regulatory subunit 1B (CKS1B)
Involvement of CKS1B in the anti-inflammatory effects of cannabidiol in experimental stroke models
In a mouse model, the anti-arthritic & anti-inflammatory effects of cannabis essential oil
Antiarthritic and Anti-Inflammatory Properties of Cannabis sativa Essential Oil in an Animal Model
In a mouse model of depression caused by unpredictable chronic stress, cannabis essential oil reduced their anxiety & depression-related behaviors
Anxiolytic and antidepressant effects of the essential oil of Moroccan Cannabis sativa in mice exposed to unpredictable chronic mild stress: Behavioral and biochemical evidences
In a rat model of anxiety, CBG modulated both a serotonin receptor & a noradrenaline receptor
Cannabigerol modulates α2-adrenoceptor and 5-HT1A receptor-mediated electrophysiological effects on dorsal raphe nucleus and locus coeruleus neurons and anxiety behavior in rat
In fish, activating CB2 receptor improved their cardiac contractile performance
Activation of the cannabinoid type 2 (CB2) receptor improves cardiac contractile performance in fish, Brycon amazonicus