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Research Roundup: Jan 23, 2024

Best of cannabinoid science this week...

On why older adults in the US are using cannabis


“Multivariable regression analyses show that marijuana use declines with age (p<.001) and is lower among women (p<.001). Marijuana use among older adults is slightly lower in states where it is illegal compared to states that have legalized (4.6% vs. 7.1%, p<.001). Use of marijuana for medical reasons increases with age; nearly two-thirds of adults 80+ who use marijuana report doing so for medical reasons. Adults 80+ also report the highest frequency of use, likely reflecting greater medical need. The most common conditions reported among adults 50+ who use marijuana for medical reasons are arthritis (61%), depression (36%), asthma (20%), and COPD (18%).

In hospice patients, cannabis combined well with opioids to reduce pain while lowering opioid usage & mitigating opioid toxicity

Medical Marijuana for Pain Management in Hospice Care as a Complementary Approach to Scheduled Opioids: A Single Arm Study

In a survey of Mexican patients with allergic respiratory diseases, the ones inhaling cannabis had less asthma

Cannabis use preferences among adult Mexican with allergic respiratory diseases: A cross-sectional study

An editorial on how seizures induced by fever may be treated by CBD via the FKBP51 protein (a stress regulator)

Cannabidiol for functional seizures (psychogenic nonepileptic seizures/attacks) and other stress-associated disorders

Cats well tolerated daily feeding of CBD at a dosage of 4 mg/kg

Healthy Cats Tolerate Long Term Daily Feeding of Cannabidiol

A review of using PEA for inflammation & immunomodulation

Therapeutic Use of Palmitoylethanolamide as an Anti-Inflammatory and Immunomodulator

A review on integrating cannabis products in the chronic pain treatment

Thoughtfully Integrating Cannabis Products Into Chronic Pain Treatment

And a review of four studies on cannabis for chronic pain

Use of cannabis and its derivates in chronic pain management: systematic review

For Parkinson's disease, a review of 95 articles on the use of cannabinoids

Beyond conventional therapy: cannabinoids as an alternative in parkinson's disease

For neuromuscular disorders, a review of the potential of the cannabinoids

Cannabinoids, Endocannabinoids, and Synthetic Cannabimimetic Molecules in Neuromuscular Disorders

A review of cannabis for the treatment of headaches

Cannabis Use in Headache Treatment: A Literature Review

A review of CBD for opioid use disorder

The Therapeutic Potential of Cannabidiol in Revolutionising Opioid Use Disorder Management

A review of the cannabinoids for mental health

Prospects for the Use of Cannabinoids in Mental Health

A review of the mechanisms that CBD uses in epilepsy to protect the brain

Enlightening Pharmacological Mechanisms of Cannabidiol in Epilepsy: A Comprehensive Review on their Neuroprotective Potential

In a mouse model of stroke, the anti-inflammatory & neuroprotective benefits of CBD involve the cyclin-dependent kinase regulatory subunit 1B (CKS1B)

Involvement of CKS1B in the anti-inflammatory effects of cannabidiol in experimental stroke models

In a mouse model, the anti-arthritic & anti-inflammatory effects of cannabis essential oil

Antiarthritic and Anti-Inflammatory Properties of Cannabis sativa Essential Oil in an Animal Model

In a mouse model of depression caused by unpredictable chronic stress, cannabis essential oil reduced their anxiety & depression-related behaviors

Anxiolytic and antidepressant effects of the essential oil of Moroccan Cannabis sativa in mice exposed to unpredictable chronic mild stress: Behavioral and biochemical evidences

In a rat model of anxiety, CBG modulated both a serotonin receptor & a noradrenaline receptor

Cannabigerol modulates α2-adrenoceptor and 5-HT1A receptor-mediated electrophysiological effects on dorsal raphe nucleus and locus coeruleus neurons and anxiety behavior in rat

In fish, activating CB2 receptor improved their cardiac contractile performance

Activation of the cannabinoid type 2 (CB2) receptor improves cardiac contractile performance in fish, Brycon amazonicus


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