Research Roundup: Jan 12, 2026
- Lex Pelger
- 11 minutes ago
- 3 min read
Best of cannabinoid science this week...
In people with cystic fibrosis, a survey found cannabis use to be common, with the reasons being “stress, insomnia/lack of sleep, and anxiety”
Evaluating the use and perceptions of cannabis and vaping post-cannabis legalisation in people with cystic fibrosis and CFTR-related disorder: survey results from a large Canadian adult cystic fibrosis clinic
In people with disabilities using cannabis, a public health survey on their reasons found the most common to be pain, tension, migraines, nausea, muscle spasms, seizures, mental health concerns & sleep disturbances.
Reasons for cannabis use among adults with disabilities: Findings from the 2023–2024 National Survey on Health and Disabilities
In people with temporomandibular disorders (jaw pain) & bruxism (teeth grinding, typically at night), a topical CBD gel lowered pain
Halloysite-Assisted Delivery of Cannabidiol for the Management of Temporomandibular Pain: A Pilot Study
In people with liver disease using cannabis, public health data found they had lower odds of in-hospital mortality, cirrhosis, chronic kidney disease & liver cancer, but higher odds of heart attack & stroke
Cannabis Use in Metabolic Dysfunction-Associated Steatotic Liver Disease Friend or Foe? A Retrospective Analysis
In Switzerland’s cannabis access study, despite high cannabis use where 25% of the people met the criteria for cannabis use disorder, the prevalence of depression & anxiety were lower than in the general population
Frequent Non-medical Cannabis Use and Mental Health: A Cross-sectional Analysis Prior to Regulated Access
On CBD & sleep quality, this review found it worked as well as melatonin at low doses & at high doses, may enhance restorative sleep stages
The Impact of Cannabidiol (CBD) on Sleep Quality: A Review of Mechanisms and Clinical Evidence
For chronic pain, a review of 25 studies compared THC & CBD ratios & found the most help for neuropathic pain
Cannabis-Based Products for Chronic Pain: An Updated Systematic Review
In pancreatitis, a review found some evidence for cannabis use linked to improved outcomes & decreased opioid usage
Cannabis use in chronic pancreatitis: A narrative review
For CBD in skincare products, a review of the data & the regulations
Cannabidiol’s Antioxidant Properties in Skin Care Products and Legislative Regulations
For metabolic regulation, a review of CBD & the effects of the endocannabinoid system
Biochemical insights into cannabidiol–endocannabinoid system interactions in the regulation of metabolic pathways
In a baby mouse model of loss of blood flow to the heart, CBD lessened the damage, oxidative stress, inflammation & the dysregulated autophagy (cellular recycling) & apoptosis (programmed cellular suicide)
Cannabidiol Protects the Neonatal Mouse Heart from Hyperoxia-Induced Injury
In a mouse model of the rare pediatric neurodegenerative disorder late infantile neuronal ceroid lipofuscinosis (CLN2), CBD delayed or eliminated seizures & extended lifespan
Chronic oral cannabidiol delays or prevents seizures in a mouse model of CLN2 disease
In a mouse model of neuropathy from chemotherapy, CBG reduced their mechanical sensitivity via the α2A-adrenoceptor
Cannabigerol reverses mechanical allodynia through α2A‐adrenergic modulation of thalamocortical signaling in chemotherapy‐induced neuropathy
In a rat model of an incisional wound, CBD lessened their mechanical hypersensitivity & they had changes to the endocannabinoid levels in their spinal cord & amygdala (emotional processing center of the brain)
The Effect of Cannabidiol on Nociceptive Behaviour and the Endocannabinoid System in an Incisional Wound Model
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