Research Roundup: Feb 3, 2026
- Lex Pelger
- Feb 2
- 2 min read
Best of cannabinoid science this week...
In people with pelvic pain & endometriosis related symptoms, a cohort study found that cannabis or CBD decreased overall pelvic pain scores, lowered levels of worst pain scores & improved quality of life scores
Perceived impact of medicinal cannabis on pelvic pain and endometriosis related symptoms in Aotearoa New Zealand: an observational cohort study
In people with migraines, CBD-rich full-spectrum oil improved migraine-related disability, headache impact, quality of life, quality of sleep & subjective well-being
Improved Migraine Disability, Sleep Quality, and Well-Being in Individuals with Chronic Migraine Self-Administering Artisanal or Industrial Full-Spectrum Cannabidiol-Rich Oils: An Observational Cohort Study
And for migraines, a review of their overlapping pathways with the endocannabinoid system (nice charts!)
Overlapping pathways of migraine and the endocannabinoid system: Potential therapeutic targets
In someone with Ewing Sarcoma (a bone cancer), after high doses of opioids could not manage the pain, just a month of medical cannabis resulted in opioid discontinuation as well as reduced systemic inflammation & the complete closure of the chronic draining fistula (a hole from the anal tract)
Ewing sarcoma-related pain: potential role of medical cannabis monotherapy in symptom management – a case report
In veterans using medical cannabis, a survey found they viewed cannabis as an important tool to cope with symptoms
In Their Own Words: A Qualitative Exploration of Veterans’ Perspectives and Experiences of Medical Cannabis Use
In people who had heart surgery, those were cannabis use disorder had lower mortality
Nationwide outcomes of cardiac surgery in patients with cannabis use disorder
For CBD & bone health, a review of 24 studies suggested a bone-protective role (with nice charts!)
Effects of Cannabidiol on Bone Health: A Comprehensive Scoping Review
For cancer pain, a review of 20 articles on the use of cannabis
Medical marijuana for management of cancer pain: a narrative review
In a mouse model of postoperative cognitive dysfunction, PEA improved short & long term memory, lowered inflammation, preserved neuronal survival, upregulated synaptic plasticity & lowered activation of the microglia (guardian immune cells of the brain)
Palmitoylethanolamide ameliorates postoperative cognitive dysfunction via microglial PPARα-mediated anti-inflammatory and neuroprotective mechanisms
In a rat model of obesity-induced inflammation, CBD reduced inflammation & the deposition of lipids
Cannabidiol mitigates high-fat-diet-induced early-stage inflammation in two adipose tissue fat depots of Wistar rats
In a neural tissue model of loss of blood flow, CBD reduced oxidative stress, protected against lipid breakdown & lowered ferroptosis (a newly discovered type of cell death mediated by iron)
Ferroptosis under fire: cannabidiol mitigates iron-dependent injury in differentiated human neuroblastoma cells following oxygen-glucose deprivation
In white blood cells, THC caused antioxidant effects
Differential Regulatory Effects of Cannabinoids and Vitamin E Analogs on Cellular Lipid Homeostasis and Inflammation in Human Macrophages
For human & canine dental plaque, full-spectrum cannabis extracts had more antimicrobial effects than CBD isolate
The Antimicrobial Activity of Plant-Derived Cannabinoid Suspensions from Cannabis sativa L. Against the Mixed Oral Microflora of Humans and Canine
In the mouth bacteria that cause cavities, THC inhibited growth & viability while decreasing the formation of biofilm (slimy aggregrations that resist treatment)
In Vitro Antimicrobial Effect of Tetrahydrocannabinol on Streptococcus mutans and Its Anticariogenic Potential
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