Research Roundup: Feb 17, 2026
- 41 minutes ago
- 2 min read
Best of cannabinoid science this week...
In people receiving medical cannabis, a meta-analysis of 64 studies found improved health-related quality of life, but many did not provide their definition of it
Health-related quality of life in patients receiving medicinal cannabis: systematic review and meta-analysis of primary research findings 2015–2025
In the Danish Medicinal Cannabis Pilot Program, interviews on their benefits for medical cannabis found that “two thirds of all patients reported a moderate to large effect”
Patients’ experiences with the use of medicinal cannabis: an international overview and findings from the Danish Medicinal Cannabis Pilot Program
In people with multiple sclerosis & treatment-resistant spasticity, nabiximols (pharmaceutical 1:1 THC:CBD spray) improved stiffness, spasms & pain
Nabiximols cannabinoid spray in treatment-resistant spasticity patients with multiple sclerosis and other aetiologies: the West of Scotland experience
In children with pediatric epilepsy, CBD caused the majority to have a 50+% reduction in seizure frequency
Adjunctive cannabidiol in intractable pediatric epilepsy: A retrospective study on tolerability, efficacy, and safety across genetic and nongenetic etiologies
For cannabis & autism, a meta-analysis of 8 studies found significant improvements in social responsiveness, adaptive behavior, hyperactivity & anxiety
Therapeutic Potential and Safety Profile of Cannabinoids in Autism Spectrum Disorder: A Systematic Review and Meta-Analysis
For neuropathic back pain, a clinical trial of a new delivery system for PEA improved pain, functional disability, sleep & quality of life
Phospholipid-Based Delivery System Optimizes the Solubility and Systemic Exposure of Palmitoylethanolamide and Supports Clinical Benefits in Chronic Neuropathic Low Back Pain
In age-related pain, a review of cannabis & the entourage effect
Therapeutic use of cannabinoids in age-related pain: Current evidence and clinical perspectives
For the blood-brain barrier & neurodegeneration, a review on the effects of the cannabinoids & the alterations the endocannabinoid system (with great charts!)
Cannabinoids, the Blood–Brain Barrier, and Neurodegeneration: Mechanisms, Dysregulation, and Therapeutic Perspectives
For strokes, a review on CBD supporting the glial cells (the support cells that make up more than half the brain volume)
Beyond neurons: Impact of cannabidiol on glial cells in ischemic stroke
For the microglia (guardian immune cells of the brain), a review of their crosstalk with the CB2 receptor for neuroinflammation & repair
Cannabinoid type 2 receptor crosstalk and microglial plasticity—shaping the balance between neuroinflammation and repair
For the organ toxicity of chemotherapy, a review of the potential of cannabinoids
Therapeutic Potential and Pharmacological Mechanisms of Cannabinoids in Alleviating Chemotherapy-Induced Organ Toxicity and Adverse Effects
In skin cancer, a review on the benefits of the cannabinoids (with great charts!)
Cannabinoids and skin cancer: Mechanistic insights, therapeutic potential, and translational perspectives
In a rat model of Alzheimer’s disease, CBD significantly enhanced cognitive function & reduced pathological changes, with protective effects comparable to the drug donepezil
Therapeutic Potential of Cannabidiol in Alleviating Cognitive Decline and Hippocampal Damage in a Rat Model of Alzheimer's Disease
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