Research Roundup: Feb 10, 2026
- Feb 9
- 2 min read
Best of cannabinoid science this week...
In people with multiple sclerosis, nabiximols (pharmaceutical 1:1 THC:CBD spray) significantly improved their sleep & sleep architecture
Nabiximols improves sleep architecture in multiple sclerosis: A prospective polysomnographic study
In children with autism & sleep disturbances, the initiation of medical cannabis increased their sleep time over an hour, with caregiver-reported improvements in sleep onset, sleep maintenance, overall sleep quality & quality of life as well as several other behavioral domains
Autism, Sleep, and Medicinal Cannabis: 18-Month Prospective Registry Outcomes on Efficacy and Safety
In an absorption test of nano CBD, being fed significantly increased bioavailability
A Randomized, Single-Dose, Single-Sequence, Two-Arm (Fasting and Fed), Open-Label Study on the Oral Pharmacokinetics of a Nanodispersible Cannabidiol Solution (150 mg/mL)
In the intestines, a review of CBD & as an antioxidant & anti-inflammatory (with lovely charts!)
The Dual Roles of Natural Cannabidiol in Combating Oxidative Stress and Inflammation: A Potential Intestinal Guardian
For PEA, a review of its myriad protective effects beyond just inflammation
Investigating properties of palmitoylethanolamide in physiology and disease: far beyond an anti-inflammatory shield
In a rat model of methamphetamine use disorder, CBD-rich hemp extracts worked better than CBD isolate in reducing relapse
A CBD-rich hemp extract is superior to CBD alone in reducing relapse to methamphetamine-seeking in rats
In a mouse model of seizures, CBG had antiseizure properties that were potentiated by CBD
Antiseizure Effects of Cannabidiol in Combination With Cannabigerol in the Maximal Electroshock Seizure Model
In a mouse model of sepsis, CBD oil lowered inflammation of the intestines, probably via the PPARα nuclear receptors that modulate genetic transcription
PPARα Expression Analysis in a Murine Model of Sepsis-like Inflammation Intestinal Tissue Treated with a Cannabidiol-Enriched Broad Spectrum Cannabis Oil
In a fruit fly model of chronic pain, CBD lowered its nociceptive (pain sensing) circuits
The parabss1 Drosophila melanogaster as Model for Chronic Nociception: Insights Into Cannabidiol Analgesic Effects
In red blood cells, CBD inhibits the PIEZO1 channels to help with blood disorders like sickle-cell disease or hereditary xerocytosis
Cannabidiol Inhibits PIEZO Channels to Mitigate Red Blood Disorders
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