Best of cannabinoid science this week...
In a study of over 3500 people, they could find no way to predict the final medical doses of CBD & THC, recommending that “Clinical guidelines should maintain a highly individual approach for cannabinoid dosing”
Can we predict the treatment doses of THC and CBD and does it matter?
https://pubmed.ncbi.nlm.nih.gov/37003923/
In 20 elite athletes, topical CBD was well tolerated & helpful in a number of domains
Topical cannabidiol is well tolerated in individuals with a history of elite physical performance and chronic lower extremity pain
https://pubmed.ncbi.nlm.nih.gov/36991501/
In a survey of women with muscular pelvic pain, the cannabis users found it effective for relieving the pain while non-cannabis users said they’d be willing to try it
Cannabis use preferences in women with myofascial pelvic pain: A cross-sectional study
In dogs stressed out by car travel or separation, one dose of CBD significantly lowered their stress-related measures A single dose of cannabidiol (CBD) positively influences measures of stress in dogs during separation and car travel https://pubmed.ncbi.nlm.nih.gov/36908527/
A positive review on using CBD for eating disorders Major approaches to cannabidiol in the treatment of binge eating and obesity: a systematic review https://ijn.zotarellifilhoscientificworks.com/index.php/ijn/article/view/282
A strong series of case studies & research reports by neuropsychopharmacology world experts on using CBD for treating brain disorders Editorial: Cannabidiol treatment in neurotherapeutic interventions, volume II https://pubmed.ncbi.nlm.nih.gov/36909164/
In multiple sclerosis, a review of the evidence showing the combination of THC & CBD reduces spasticity
Use of cannabis medicine for the treatment of spasticity-associated pain
Plus this fMRI study of how this combination changes brain connectivity
Resting-state functional connectivity in multiple sclerosis patients receiving nabiximols for spasticity
In mice exposed to the persistent organic pollutant perfluorooctane sulfonate, CBD protected the kidney cells from death via its antioxidant effects Perfluorooctane sulfonate-induced apoptosis in kidney cells by triggering the NOX4/ROS/JNK axis and antagonism of cannabidiol https://pubmed.ncbi.nlm.nih.gov/36988283/