Research Roundup: Mar 31, 2026
- Mar 30
- 2 min read
Best of cannabinoid science this week...
In children with drug-resistant epilepsies, CBD caused clinically relevant seizure reduction & improved quality of life, especially sleep quality
4CPS-011 Paediatric drug-resistant epilepsies: efficacy, tolerability, and safety of add-on cannabidiol
And for treatment-resistant epilepsy, the responders to CBD treatment had increased network integration & network segregation
Global brain network dynamics predict therapeutic responsiveness to cannabidiol treatment for refractory epilepsy
For the link between cannabis consumption & problematic Internet use, a survey found both positive & negative effects
Cannabis consumption and problematic internet use: analysis of a free-text response collected through a self-reported online questionnaire
In frequent cannabis users, they had no cognitive impairments when tested 12 hours after their last ingestion
Cognitive performance and subjective effects the morning after last use of smoked cannabis by adults who use cannabis frequently: An observational study
In people with heart failure, public health data found no difference in mortality between cannabis users & non-users
Association of Cannabis use and Survival in patients with heart failure: A claims-based cohort study of commercially insured adults
For CBD use by small animal veterinarians, a survey found a high frequency of use in dogs & cats, with the most common reason being for cancer, chronic pain, behavioral changes, stress & anti-inflammation
Assessment of Cannabidiol Supplements Use in Small Animals Practice in Portugal
“Additionally, in an open‐answer question, some respondents referred to the use of CBDS for other purposes, namely: cognitive dysfunction, appetite stimulant, feline gingivostomatitis, geriatric animals, senility and wound healing. The most frequent adverse effects were hypersialia/sialorrhea (28%; 44/158) and apathy (25%; 39/158)”.
On CBD & the mitochondria (powerhouse of the cell), a lovely review on the effects in different diseases (with a set of charts that will make your heart sing)
The Therapeutic Crossroad Between Mitochondria and Cannabidiol: A Mini-Review
In Parkinson’s disease, a review of the cannabinoids from preclinical & clinical data (with a nice chart)
Cannabinoids and cognition in Parkinson’s disease: Insights from animal models and emerging clinical evidence
For osteoarthritis, this review of 19 studies found the strongest data for CBD
The role of cannabis-based medicinal products (CBMPs) in managing osteoarthritis symptoms: a scoping review of current evidence and future directions
In obsessive-compulsive disorder, a review of 13 studies on the involvement of the endocannabinoid system
The Endocannabinoid System in Obsessive-Compulsive Disorder: A Scoping Review
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