Best of cannabinoid science this week...
In people with alcohol use disorder, CBD reduced self-reported anxiety during alcohol cue exposure, reduced alcohol craving & increased activation of the parasympathetic nervous system (your relaxation system)
Cannabidiol alters psychophysiological, craving and anxiety responses in an alcohol cue reactivity task: A cross‐over randomized controlled trial
In healthy humans, a high-fat meals significantly increases the bioavailability of CBD
A high-fat meal significantly impacts the bioavailability and biphasic absorption of cannabidiol (CBD) from a CBD-rich extract in men and women
For Parkinson's disease, a case series of using cannabinoids for the non-motor symptoms like cognitive impairment, insomnia & daytime sleepiness
Low Doses of Cannabis Extract Ameliorate Non-Motor Symptoms of Parkinson's Disease Patients: A Case Series
https://www.frontiersin.org/journals/human-neuroscience/articles/10.3389/fnhum.2024.1466438/abstract
For the neuroinflammation after stroke, a review on how cannabinoids reduced neuroinflammation, cell death & neurological deficits
The Effects of Cannabinoids on Ischemic Stroke-Associated Neuroinflammation: A Systematic Review
For the antimicrobial properties of the cannabinoids, a review of developments over the last five years
Antimicrobial Potential of Cannabinoids: A Scoping Review of the Past 5 Years
For hormones, a review of the effects of the cannabinoids (a lot of charts)
Relationship of the Endocannabinoid System with Hormonal Functions
In the cognitive impairments from sleep loss, a review of the ability of the terpene beta caryophyllene to reduce the associated inflammation, oxidative stress, neuronal death & reduced neuroplasticity
Exploring β-caryophyllene: a non-psychotropic cannabinoid's potential in mitigating cognitive impairment induced by sleep deprivation
In a mouse model of alcohol use disorder, CBD reduced alcohol intake
Cannabidiol dose-dependently reduces alcohol intake in mice via a non-5-HT1A receptor mechanism: Exploration of other potential receptor targets
In brain cells, CBD increased tau protein degradation (related to Alzheimer's disease) via increased autophagy (cellular recycling)
Cannabidiol-Induced Autophagy Ameliorates Tau Protein Clearance
In skin cells, long-term exposure of CBD enhanced their growth & caused antioxidant, anti-aging & wound healing activities as well as enhanced collagen production
Discovering the Potential of Cannabidiol for Cosmeceutical Development at the Cellular Level
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