Best of cannabinoid science this week...
In a double-blind study of patients with periodontitis (gum disease), CBD improved gingival bleeding & gingival scores as well as reducing inflammation in human gingival cells
Phytocannabinoids and gingival inflammation: Preclinical findings and a placebo-controlled double-blind randomized clinical trial with cannabidiol
In patients with plasma cell disorders such as the cancer myeloma, a survey found that they used cannabinoids for pain, sleep, depression & stress reduction
Cannabis and Cannabinoid Use and Perceptions in Patients with Plasma Cell Disorders: A National Healthtree Foundation for Multiple Myeloma Survey
In older adult cancer survivors, a survey found they used cannabis for pain & insomnia
Cannabis Perceptions and Patterns of Use Among Older Adult Cancer Survivors
For spasticity, 2 case reports of using cannabinoids [Portuguese]
USO DOS FITOCANABINÓIDES PARA TRATAMENTO DE ESPASTICIDADE MUSCULAR: RELATO DE CASO
In asthmatics, no association between cannabis use & an asthma attack
Asthma episode/attack risk by smoking status, self-reported gender, educational attainment, e-cigarette usage and exposure to marijuana smoke
In rotator cuff surgery patients, the use of CBD caused no deficits after a year of follow-up
Cannabidiol for Postoperative Pain Control After Arthroscopic Rotator Cuff Repair Demonstrates No Deficits in Patient-Reported Outcomes Versus Placebo: 1-Year Follow-up of a Randomized Controlled Trial
In cats, CBD seemed effective for easing separation anxiety
Is cannabidiol (CBD) effective to ease separation anxiety?
Also in canine blood immune cells, CBD or THC combined well with the commonly used dug dexamethasone & may be used to lower its dosage & side effects
Potential to use cannabinoids as adjunct therapy for dexamethasone: An in vitro study with canine peripheral blood mononuclear cells
For CBD, a review of the many mechanisms it uses for its therapeutic effects
A systematic review of molecular mechanism and therapeutic effect of Cannabidiol (CBD)
For head & neck conditions, CBD is suggested for obstructive sleep apnea, chronic pain, nausea & coughing
Cannabidiol (CBD): Potential Use in Otorhinolaryngology
In a rat model of obsessive-compulsive disorder resulting from epilepsy, CBD improved their symptoms in a gender-dependent manner
CBD treatment following early life seizures alters orbitofrontal-striatal signaling during adulthood
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In a pig model of skin burns, a full spectrum cannabis oil with low THC & CBD decreased inflammation & reduced burn wound progression
Topical Noneuphoric Phytocannabinoid Elixir 14 Reduces Inflammation and Mitigates Burn Progression
In young rats, CBD lessened damage from brain hemorrhages via protection of the blood brain barrier & lowering of inflammation, excitotoxicity & oxidative stress
Cannabidiol reduces intraventricular hemorrhage brain damage, preserving myelination and preventing blood brain barrier dysfunction in immature rats
In a mouse model of bleeding around the brain, CBD lowered mortality rates & brain immune cell activation
Cannabidiol as a Therapy for Experimental Subarachnoid Hemorrhage
In a rat model of neuroinflammation from a high-fat diet, CBD lowered inflammation in the cerebral cortex via the reduction of lipid inflammation
Anti-inflammatory effects of cannabidiol in early stages of neuroinflammation induced by high-fat diet in cerebral cortex of rats
In a tissue model of food allergies, THC decreased the associated IgE antibodies
Inhibition of IgE production in Plasma Cell Line by Cannabinoid-Containing Product Associated with Regulation of XBP-1 and IgE heavy chain expression