Best of cannabinoid science this week...
In a survey of postmenopausal women experiencing orgasmic dysfunction, the majority stated that cannabis helped with orgasm with the injection methods including smoking, vaping, edibles & topical applications
USE AND PERCEIVED IMPACT OF CANNABIS ON ORGASM IN POST MENOPAUSE WOMEN
In a survey of people in the UK with spinal cord injuries, the majority used street cannabis to manage their chronic pain, spasticity, difficulty in sleeping & anxiety/depression
Cannabis use by individuals with spinal cord injury in the UK: a call for improved patient education and physician awareness for pain and spasticity management
For refractory epilepsy, a case study of using CBD & meditation
Patient experiential knowledge and CAM: a case study of refractory epilepsy patients in France
A review of public health data on cannabis use in the UK found that young people were more likely to report sleep improvements
Prescribed Medical Cannabis Use Among Older Individuals: Patient Characteristics and Improvements in Well-Being: Findings from T21
For athletes & CBD, a review of 18 studies on the ability of CBD to be anti-inflammatory, anti-anxiety, neuroprotective & painkilling as well as protecting the GI system from the damage of inflammation & for the healing of traumatic skeletal injuries
Nutrological modulation of cannabidiol in the inflammatory processes of athletes: a systematic review
For psoriasis, a review of using CBD
The Perspective of Cannabidiol in Psoriasis Therapy
For autism, a review of 77 studies on targeting the endocannabinoid & cholinergic systems
Targeting cholinergic and endocannabinoid system as a therapeutic intervention for core asd associated phenotypes in autism model: a systematic review
For obesity & weight loss, a review of the endocannabinoid system’s effects
The circulating and central endocannabinoid system in obesity and weight loss
A review of treating various neuropathologists with cannabis
Assessing effects of Cannabis on various neuropathologies: A systematic review
In a rat model of liver cirrhosis, CBD protected the liver from changes in liver enzyme levels, scarring & cell death
Hepatoprotective Effect of Cannabidiol on the Progression of Experimental Hepatic Cirrhosis in Rats
In a mouse model of Alzheimer's disease, CBD protected the neurons of the hippocampus (memory center of the brain) from the amyloid plaques
Cannabidiol protects mouse hippocampal neurons from neurotoxicity induced by amyloid β-peptide25-35
In a mouse model of chronic neuropathic pain, CBN relieved the pain while CBDV, CBG, THCV & delta-8 THC showed cannabimimetic activity (cannabis-like effects)
Select Minor Cannabinoids from Cannabis sativa are Cannabimimetic and Antinociceptive in a Mouse Model of Chronic Neuropathic Pain
In a rat model of obesity, a thesis project on using oleoylethanolamide to alter the oxytocin system & its effects on olfactory clues, food stimuli & social memory as well as the transcription of genes related to inflammation & neural plasticity
Pre-clinical evaluation of novel pharmacological targets for the treatment of obesity and eating disorders: focus on Oleoylethanolamide and the oxytocinergic system
https://iris.uniroma1.it/handle/11573/1711872 And for calcification of your vascular system (a risk factor for cardiovascular disease), oleoylethanolamide activated the STING1 signaling system to reduce calcification, cellular aging & damage to the mitochondria (powerhouse of the cell)
STING1-accelerated vascular smooth muscle cell senescence-associated vascular calcification in diabetes is ameliorated by oleoylethanolamide via improved mitochondrial DNA oxidative damage
In neurons, CBN displayed no cytotoxic effects while causing changes to a number of gene’s expression
Cannabinol Regulates the Expression of Cell Cycle-Associated Genes in Motor Neuron-like NSC-34: A Transcriptomic Analysis
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