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Research Roundup: Feb 26, 2024

Best of cannabinoid science this week...

A secret buyer survey out of Hungary finds only half the CBD products analyzed to be correctly labeled for their CBD concentration

Safety and risks of CBD oils purchased online: unveiling uncertain quality and vague health claims

In people with migraines, 600 mg of PEA resolved headaches, lowered pain & reduced rescue medication significantly more than a placebo with no adverse events

Effectiveness of Palmitoylethanolamide (Levagen+) Compared to a Placebo for Reducing Pain, Duration, and Medication Use during Migraines in Otherwise Healthy Participants—A Double-Blind Randomised Controlled Study

“Overall, PEA was safe and effective in reducing migraine pain, duration, and medication use in an otherwise healthy adult population.”

A review of how PEA reduced the eye’s intraocular pressure for glaucoma

Evaluation of the nutraceutical Palmitoylethanolamide in reducing intraocular pressure (IOP) in patients with glaucoma or ocular hypertension: a systematic review and meta-analysis

In a naturalistic study of patients with depression, cannabis caused a clinically significant reduction of depression severity & was found to be well tolerated with a dropout rate comparable to those in clinical trials of antidepressant medication

Effectiveness of Medical Cannabis for the Treatment of Depression: A Naturalistic Outpatient Study

From a pediatric palliative care clinic, a case report of the benefits of medical cannabis for spasticity, seizures & cancer symptoms

Experience With Medical Marijuana in a Pediatric Palliative Care Clinic: Case Report

A case report of a dog using CBD-rich full-spectrum oil to treat the common autoimmune skin disease discoid lupus erythematosus

Case report: Cannabinoid therapy for discoid lupus erythematosus in a dog

In a double-blind driving study of people with Tourette syndrome & tic disorders, treatment with nabiximols (1:1 THC:CBD) did not impair their driving skills & even improved fitness to drive in a subset of patients who were unfit to drive before treatment

The Effect of Nabiximols on Driving Ability in Adults with Chronic Tic Disorders: Results of a Substudy Analysis of the Double-Blind, Randomized, Placebo-Controlled CANNA-TICS Trial

An overview of cannabis-based medicines for chronic pain

Overview: Chronic Pain and Cannabis-Based Medicines

And for pain, an updated review of THC & CBD

Tetrahydrocannabinol and Cannabidiol for Pain Treatment—An Update on the Evidence

In a rat model of juvenile diabetes, CBD helped to control blood glycemia, body weight & to improve insulin levels to close to normal values

Efficacy And Safety of Cannabidiol on Juvenile Diabetes Outcomes in Male Rats

In a mouse model epilepsy, CBD protected against neuronal death from overreactive astrocytes (brain support cells)

Cannabidiol protects against neurotoxic reactive astrocytes-induced neuronal death in mouse models of epilepsy


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